Land is the most important physical basis for the existence and development of the human being. With the growth of population and the rapid development of industrialization and urbanization, the shortage of land resources is becoming more and more serious. It has been felt that land must be used rationally. Now the optimal allocation of land resources is becoming a significant study task, and the land use and land cover change study plan, which is attached importance recently by academe, can offer support and accelerate each other. Therefore, how to understand their relationship and make use of the relationship effectively becomes the key problem. It not only can help the study of land use and land cover change but also is important to the optimal allocation of land resources. In this paper, the main aim and content of LUCC are firstly introduced and analyzed. Based on the analysis, the way of connecting land use and land cover change with regional optimal allocation of land resources is discussed systematically. It presents that land use and land cover change study can offer data, theory and technology support to the study of land resource optimal allocation, and at the same time, the study of land resource optimal allocation can make the study of land use and land cover change deeply and profoundly. The connection of them can promote the sustainable land use.