Arable land is soul of land resource, and the dynamic change and rational utilization of arable land are the key problems that affect sustainable development of region. The natural disaster is very serious in Heilonggang region whose natural conditions such as water and soil are the poorest in Huang-Huai-Hai Plain. With the economic development and population growth, a great amount of arable land has been lost and the contradiction of land shortage has become more serious which restricts regional sustainable development. This paper has revealed the basic process and regional difference according to the data of long-series statistics of arable land area during the past 50 years and the detailed-investigation of land use during the recent five years. Further, evaluation of sustainable utilization on arable land is discussed. The results show that there is a trend of obvious fluctuant decrease in arable land area during the past 50 years. The changes of arable land area undergo the process from increase to steep decrease to gently decrease. During the process, there are two height periods of decrease in arable land: 1955to 1958 and 1965 to 1978, respectively. The sustainable utilization of arable land in Heilonggang region is critical, with synthetical index of 48 25.