In this paper, the characteristics of the integrality and relativity, the sectionality and differentiality, the hierarchy and network, and the opening and dissipation of spatial economy of basin were described. The principles of system, synthesis, regionalization, tridimensional network, and water resource centered basin exploration were analyzed. A model of Point axis region gradual exploration was proposed. The essential idea of the model is to strengthen the economic and technologic energy of point and axis, guided by the model of regional growth and economic development and taking the point and axis exploration to be the important formation of basin development. So the national resources of whole basin can be fully explored and utilized.