This paper highlights the application and development of geographic information system in the past more than thirty years, briefs the progress in GIS software technique, introduces the deepening of the geo information mechanisms, self organization, self correlation theory and temporal spatial thematic high dimensional data model as well as studies comprehensive integrated technical system centered around GIS at the turn of the 21st century. It also discusses information times and network world in the new century and points out in the rapid development of high & new technologies such as “information expressway”, “digital earth”, in depth study and application of GIS should be included in the State information technology development planning, so as to make GIS offer deepening and all directional service to the national sustainable development and global change studies.