In order to develop indicator system of regional land for land sustainable use, structures and functions of regional land use system, as well as objects of regional land for sustainable use, must be intensively understood; land sustainable use level, coordinative development and interactional status in different regions should be accurately reflected. Hereby, this paper selects typical sensitive indicators, which are independent and reflect the features in all aspects, to design the frame of indicator system of regional land for sustainable use, including object level, rule level, factor level and element level. The object level shows acting rule of land use system from the macroscopical level and reflects whole situation of regional land sustainable use. The rule level is the disintegration of the object level, and ulteriorly declare the act and impact of each aspects in land use system for regional land sustainable use, including productivity, protection, security, viability and acceptability. The factor level clues in the act and impact of every part in land use system, and every evaluated factor is concretely delivered by some elements. The element level is the smallest unit of this indicator system, and as the basic indicator describing evaluated factors, is the concrete measurement of sustainable land use degree in this indicator system.